Enalapril
| Evidence Level: N/A | Predicted Indications: 0 |
Table of Contents
- Enalapril
Enalapril: Known uses and market status in Australia
Summary
The TxGNN model’s candidates for Enalapril (score ≥ 0.99) are all known uses, so there is currently no new predicted indication. The one candidate that can be traced to a source matches an approved use from a licence in another country. This page lists those known uses and the market status in Australia.
Quick overview
| Item | Content |
|---|---|
| New predicted indications | None (all traceable model candidates are known uses) |
| Known uses among model candidates | 1 |
| Evidence level | Not applicable |
| Australia Market Status | Listed on the PBS Schedule (1 of 1 items) – TGA (ARTG) registration status is not included in this data |
| Number of PBS Items | 1 (valid: 1) |
Known uses among the model’s candidates
Approved (supported by a licence or label)
| Indication | Source |
|---|---|
| congestive heart failure | licence in another country (approved indication: heart failure) |
Related to an approved indication (same disease category)
| Indication | Approved category |
|---|---|
| none | none |
Relations recorded in the knowledge graph (no approval found)
| Indication |
|---|
| none |
Australia Market Information
| Licence | Product | Dosage form | Status |
|---|---|---|---|
| 13369P | APO-Enalapril | Tablet containing enalapril maleate 5 mg | Valid |
Safety Considerations
- Contraindication-related conditions (from the TxGNN knowledge graph, not label text): angioedema in several forms, including acquired, hereditary (including C1-inhibitor deficiency), non-histaminic, and renin-angiotensin-aldosterone system blocker-induced angioedema.
- Drug interactions: the interaction database returned 100 entries.
- Major: potassium citrate and potassium bicarbonate.
- Moderate (examples): metformin and other glucose-lowering drugs (alogliptin, linagliptin, canagliflozin, dapagliflozin, empagliflozin, chlorpropamide), corticosteroids (hydrocortisone, dexamethasone, betamethasone, budesonide, triamcinolone), acetylsalicylic acid, morphine, bupropion, dronabinol, picosulfuric acid, and polyethylene glycol with electrolytes.
Warnings and contraindications from the label were not available. Please refer to the TGA-approved Product Information (PI) for full safety information.
Disclaimer
This content is for research purposes only and does not constitute medical advice. Clinical validation is required before any clinical application.