AuTxGNN
Drug repurposing predictions for Australia using the TxGNN graph neural network.
Australia: what this site covers
This site publishes reports for 749 medicines listed on the PBS Schedule (Australia).
This site’s local data
| Item | Detail |
|---|---|
| Dataset | PBS Schedule items (current schedule, CSV) |
| Publisher | Australian Department of Health, PBS public API |
| Download | https://data-api.health.gov.au/pbs/api/v3/items (API documentation: https://data.pbs.gov.au/api/api-public.html) |
| Item identifier | PBS item code |
| Updates | Automatic weekly download (every Monday) of the schedule currently in effect; an item that drops off the list keeps its previous status |
Details: Data Sources.
Reports by evidence level:
| Evidence level | Reports | Share |
|---|---|---|
| L1 | 10 | 1.3% |
| L2 | 31 | 4.1% |
| L3 | 21 | 2.8% |
| L4 | 45 | 6.0% |
| L5 | 484 | 64.6% |
| N/A | 158 | 21.1% |
4 predicted drug–disease pairs on this site appear on no other of the 30 TxGNN sites.
Highest evidence levels on this site
| Medicine | Evidence level |
|---|---|
| Bendamustine | L1 |
| Busulfan | L1 |
| Peginterferon Alfa-2A | L1 |
| Clomipramine | L1 |
| Doxorubicin | L1 |
| Ranitidine | L1 |
| Potassium | L1 |
| Atorvastatin | L1 |
| Tacrolimus | L1 |
| Dapsone | L1 |
Medicines covered only by this site among the 30 TxGNN sites
| Medicine | Evidence level |
|---|---|
| Perhexiline | L5 |
| Alogliptin | N/A |
| Aluminium | N/A |
| Bivalirudin | N/A |
| Castor Oil | N/A |
| Chloroform | N/A |
| Citrulline | N/A |
| Dicloxacillin | N/A |
| Dornase Alfa | N/A |
| Ibandronate | N/A |
| Idarubicin | N/A |
| Lanthanum Carbonate | N/A |
| Lercanidipine | N/A |
| Phenelzine | N/A |
| Pizotifen | N/A |
Overview
AuTxGNN uses graph neural networks to identify potential new therapeutic uses for existing drugs registered with the Australian Therapeutic Goods Administration (TGA).
Data Sources
- Drug Data: PBS Schedule (Pharmaceutical Benefits Scheme)
- Knowledge Graph: TxGNN biomedical knowledge graph
- Clinical Trials: ClinicalTrials.gov, ANZCTR (Australian New Zealand Clinical Trials Registry)
- Literature: PubMed, Google Scholar
API Access
FHIR R4 API
Access prediction data via FHIR R4 resources:
- Base URL:
https://autxgnn.yao.care/fhir - Capability Statement: /fhir/metadata
Available Resources
| Resource Type | Description |
|---|---|
| MedicationKnowledge | Drug information from the PBS Schedule |
| ClinicalUseDefinition | Predicted drug-disease indications |
Disclaimer
Research Use Only: The predictions provided by AuTxGNN are for research purposes only and do not constitute medical advice. All drug repurposing candidates require clinical validation before any therapeutic application.
This is not a TGA-approved tool. Always consult healthcare professionals for medical decisions.
Contact
- Website: yao.care
- GitHub: yao-care/AuTxGNN
Last updated: 2026-11-04
About the Developer
This platform is developed and operated by 藥提醒科技有限公司 (yao.care). See the About page for the full company and methodology background.