AuTxGNN

Drug repurposing predictions for Australia using TxGNN knowledge graph.

Overview

AuTxGNN uses graph neural networks to identify potential new therapeutic uses for existing drugs registered with the Australian Therapeutic Goods Administration (TGA).

Data Sources

• Drug Data: Australian Register of Therapeutic Goods (ARTG)
• Knowledge Graph: TxGNN biomedical knowledge graph
• Clinical Trials: ClinicalTrials.gov, ANZCTR (Australian New Zealand Clinical Trials Registry)
• Literature: PubMed, Google Scholar

API Access

FHIR R4 API

Access prediction data via FHIR R4 resources:

• Base URL: https://autxgnn.yao.care/fhir
• Capability Statement: /fhir/metadata

Available Resources

Resource Type	Description
MedicationKnowledge	Drug information from ARTG
ClinicalUseDefinition	Predicted drug-disease indications

Disclaimer

Research Use Only: The predictions provided by AuTxGNN are for research purposes only and do not constitute medical advice. All drug repurposing candidates require clinical validation before any therapeutic application.

This is not a TGA-approved tool. Always consult healthcare professionals for medical decisions.

Contact

• Website: yao.care
• GitHub: yao-care/AuTxGNN

---

Last updated: 2026-03-26