Kaolin
| Evidence Level: N/A | Predicted Indications: 0 |
Table of Contents
- Kaolin
Kaolin: Known uses and market status in Australia
Summary
The TxGNN model has no candidate with a score of 0.99 or higher for Kaolin, so there is currently no new predicted indication. The drug’s own recorded uses are listed below; at present none are recorded for this drug.
Quick overview
| Item | Content |
|---|---|
| New predicted indications | None (no model candidate scored 0.99 or higher) |
| Known uses recorded for this drug | 0 |
| Evidence level | Not applicable |
| Australia Market Status | Listed on the PBS Schedule (1 of 1 items) – TGA (ARTG) registration status is not included in this data |
| Number of PBS Items | 1 (valid: 1) |
Known uses recorded for this drug
Approved (supported by a licence or label)
| Indication | Source |
|---|---|
| none | none |
Related to an approved indication (same disease category)
| Indication | Approved category |
|---|---|
| none | none |
Relations recorded in the knowledge graph (no approval found)
| Indication |
|---|
| none |
Australia Market Information
| Licence | Product | Dosage form | Status |
|---|---|---|---|
| 7348R | nan | nan | Valid |
Safety Considerations
Drug Interactions: The data compiled for this report list 84 interactions. The first 20 retrieved include:
- Major: dolutegravir, bictegravir
- Moderate: doxycycline, tetracycline, alendronic acid, risedronic acid, ibandronate, allopurinol, proguanil, atropine, baloxavir marboxil, and opioids (codeine, dihydrocodeine, morphine, benzhydrocodone, butorphanol)
- Minor: beta-blockers (acebutolol, atenolol, betaxolol, bisoprolol)
Kaolin is an adsorbent, which is consistent with reduced absorption of co-administered oral drugs. This is an inference, not stated in the data. Separating administration times is therefore worth considering.
Other safety signals from the retrieved literature:
- Inhaled kaolin dust is associated with pneumoconiosis (kaolinosis).
- A 1971 report describes coagulation defects after intravenous kaolin.
- Because kaolin is pro-coagulant, use in a thrombotic or hypercoagulable condition could be harmful.
Please refer to the TGA-approved Product Information (PI) for warnings and contraindications, as none were available for this report.
Disclaimer
This content is for research purposes only and does not constitute medical advice. Clinical validation is required before any clinical application.