Valaciclovir

Evidence Level: N/A

Predicted Indications: 0

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Table of Contents

1. Valaciclovir
   1. Pharmacist Assessment Report
   2. Valaciclovir: Known uses and market status in Australia
   3. Summary
   4. Quick overview
   5. Known uses recorded for this drug
      1. Approved (supported by a licence or label)
      2. Related to an approved indication (same disease category)
      3. Relations recorded in the knowledge graph (no approval found)
   6. Australia Market Information
   7. Safety Considerations
   8. Disclaimer

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Pharmacist Assessment Report

Valaciclovir: Known uses and market status in Australia

Summary

The TxGNN deep-learning model has no candidate with a score of 0.99 or higher for Valaciclovir, so there is currently no new predicted indication. The drug’s own recorded uses are listed below. They are not model candidates.

Quick overview

Item	Content
New predicted indications	None (no model candidate scored 0.99 or higher)
Known uses recorded for this drug	4
Evidence level	Not applicable
Australia Market Status	Listed on the PBS Schedule (1 of 1 items) – TGA (ARTG) registration status is not included in this data
Number of PBS Items	1 (valid: 1)

Known uses recorded for this drug

Approved (supported by a licence or label)

Indication	Source
herpes	licence in another country
herpes simplex	licence in another country
herpes zoster	licence in another country
viral infection	licence in another country

Related to an approved indication (same disease category)

Indication	Approved category
none	none

Relations recorded in the knowledge graph (no approval found)

Indication
none

Australia Market Information

Licence	Product	Dosage form	Status
5480K	Valtrex	Tablet 500 mg (as hydrochloride)	Valid

Safety Considerations

• Drug Interactions: 100 potential interactions were identified in the interaction database searched. The main ones listed at Moderate level are:
  • Aminosalicylates: mesalazine, balsalazide, olsalazine, sulfasalazine
  • Aminoglycosides and related antibiotics: paromomycin, neomycin, streptomycin
  • Trospium

  Cimetidine is listed at Minor level. Several others (for example calcitriol, pantoprazole, glimepiride, doxycycline, metformin, omeprazole, morphine) are listed with unknown severity.

• Renal considerations: Valaciclovir/acyclovir requires renal dose adjustment, which is relevant to any future evaluation in patients with renal impairment.

For warnings and contraindications, please refer to the TGA-approved Product Information (PI).

Disclaimer

This content is for research purposes only and does not constitute medical advice. Clinical validation is required before any clinical application.

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